Stem Cell Commons

The Stem Cell Commons is a repository of data belonging to members of the Harvard Stem Cell Institute (HSCI).

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1 to 10 of 26 Results

Zon Lab(Harvard University) Oct 30, 2020
A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis Oct 30, 2020 - Zon Lab Paik, Elizabeth J.; Mahony, Shaun; White, Richard M.; Price, Emily N.; DiBiase, Anthony; Dorjsuren, Bilguujin; Mosimann, Christian; Davidson, Alan J.; Gifford, David; Zon, Leonard I., 2020, "A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis", https://doi.org/10.7910/DVN/0XYJJW, Harvard Dataverse, V1 Deletion of caudal/cdx genes alters hox gene expression and causes defects in posterior tissues and hematopoiesis. Yet, the defects in hox gene expression only partially explain these phenotypes. To gain deeper insight into Cdx4 function, we performed ChIP-seq combined with gene...
a_16131.txt Oct 30, 2020 - A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis Plain Text - 3.7 KB - MD5: ffa68dc867f4d3ae669d81897879ce5b Assay metadata
i_16131.txt Oct 30, 2020 - A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis Plain Text - 7.2 KB - MD5: 37f65eed43f0c5d4eaef1911d25219c4 Investigation metadata
s_16131.txt Oct 30, 2020 - A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis Plain Text - 1.5 KB - MD5: 57c08177b2f6fdbf5c3228a280db8852 Study metadata
Orkin Lab(Harvard University) Oct 30, 2020
ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells Oct 30, 2020 - Orkin Lab Pinello, Luca; Xu, Jian; Orkin, Stuart H.; Yuan, Guo-Cheng, 2020, "ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells", https://doi.org/10.7910/DVN/FFPCJX, Harvard Dataverse, V1 We report a computational approach for investigation of chromatin state plasticity. We applied this approach to investigate an ENCODE ChIP-seq dataset profiling the genome-wide distribution of H3K27me3 in 19 human cell lines. We found that high plasticity regions (HPRs) can be di...
a_15621.txt Oct 30, 2020 - ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells Plain Text - 2.6 KB - MD5: cbd7837b8da6960e2af8cb2e96307533 Assay metadata
i_15621.txt Oct 30, 2020 - ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells Plain Text - 6.2 KB - MD5: 03c6861209360f918b631f6b15c4bffd Investigation metadata
s_15621.txt Oct 30, 2020 - ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells Plain Text - 2.1 KB - MD5: 04048e74a486c0866cf1709abec3f18e Study metadata

Zon Lab(Harvard University)

Oct 30, 2020

A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis

Oct 30, 2020 - Zon Lab

Paik, Elizabeth J.; Mahony, Shaun; White, Richard M.; Price, Emily N.; DiBiase, Anthony; Dorjsuren, Bilguujin; Mosimann, Christian; Davidson, Alan J.; Gifford, David; Zon, Leonard I., 2020, "A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis", https://doi.org/10.7910/DVN/0XYJJW, Harvard Dataverse, V1

Deletion of caudal/cdx genes alters hox gene expression and causes defects in posterior tissues and hematopoiesis. Yet, the defects in hox gene expression only partially explain these phenotypes. To gain deeper insight into Cdx4 function, we performed ChIP-seq combined with gene...

a_16131.txt

Oct 30, 2020 - A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis

Plain Text - 3.7 KB -

Assay metadata

i_16131.txt

Oct 30, 2020 - A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis

Plain Text - 7.2 KB -

Investigation metadata

s_16131.txt

Oct 30, 2020 - A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis

Plain Text - 1.5 KB -

Study metadata

Orkin Lab(Harvard University)

Oct 30, 2020

ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells

Oct 30, 2020 - Orkin Lab

Pinello, Luca; Xu, Jian; Orkin, Stuart H.; Yuan, Guo-Cheng, 2020, "ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells", https://doi.org/10.7910/DVN/FFPCJX, Harvard Dataverse, V1

We report a computational approach for investigation of chromatin state plasticity. We applied this approach to investigate an ENCODE ChIP-seq dataset profiling the genome-wide distribution of H3K27me3 in 19 human cell lines. We found that high plasticity regions (HPRs) can be di...

a_15621.txt

Oct 30, 2020 - ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells

Plain Text - 2.6 KB -

Assay metadata

i_15621.txt

Oct 30, 2020 - ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells

Plain Text - 6.2 KB -

Investigation metadata

s_15621.txt

Oct 30, 2020 - ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells

Plain Text - 2.1 KB -

Study metadata

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