1 to 3 of 3 Results
Oct 30, 2020 - Orkin Lab
Xu, Jian; Zhen, Shao; Glass, Kimberly; Bauer, Daniel E.; Pinello, Luca; Van Handel, Ben; Hou, Serena; Stamatoyannopoulos, John A.; Mikkola, Hanna K.A.; Yuan, Guo-Cheng; Orkin, Stuart H., 2020, "Comparative profiling of chromatin state maps and transcription factor occupancy during human fetal and adult erythropoiesis [Histone Modification]", https://doi.org/10.7910/DVN/Z6OX6R, Harvard Dataverse, V1
Gene-distal enhancers are critical for tissue-specific gene expression, but their genomic determinants within a specific lineage at different stages of development are unknown. Here we profile chromatin state maps, transcription factor occupancy, and gene expression profiles duri... |
Oct 30, 2020 - Orkin Lab
Xu, Jian; Zhen, Shao; Glass, Kimberly; Bauer, Daniel E.; Pinello, Luca; Van Handel, Ben; Hou, Serena; Stamatoyannopoulos, John A.; Mikkola, Hanna K.A.; Yuan, Guo-Cheng; Orkin, Stuart H., 2020, "Comparative profiling of chromatin state maps and transcription factor occupancy during human fetal and adult erythropoiesis [Transcription Factor Binding]", https://doi.org/10.7910/DVN/P75S6Z, Harvard Dataverse, V1
Gene-distal enhancers are critical for tissue-specific gene expression, but their genomic determinants within a specific lineage at different stages of development are unknown. Here we profile chromatin state maps, transcription factor occupancy, and gene expression profiles duri... |
Oct 30, 2020 - Orkin Lab
Pinello, Luca; Xu, Jian; Orkin, Stuart H.; Yuan, Guo-Cheng, 2020, "ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells", https://doi.org/10.7910/DVN/FFPCJX, Harvard Dataverse, V1
We report a computational approach for investigation of chromatin state plasticity. We applied this approach to investigate an ENCODE ChIP-seq dataset profiling the genome-wide distribution of H3K27me3 in 19 human cell lines. We found that high plasticity regions (HPRs) can be di... |