11 to 20 of 26 Results
Oct 30, 2020 -
Identification of genes regulated by Rcor1 in CD71+, TER119- erythroid progenitors using mRNA-seq analysis
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MD5: 70fc8d734627d5903b632fb2bf50ef86
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Oct 30, 2020 -
Identification of genes regulated by Rcor1 in CD71+, TER119- erythroid progenitors using mRNA-seq analysis
Plain Text - 1.8 KB -
MD5: 24c528062141dc01a93ff5e72c83a1fb
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Oct 30, 2020 - Orkin Lab
Kerenyi, Marc A.; Zhen, Shao; Hsu, Yu-Jung; Guoji, Guo; Sidinh, Luc; O’Brien, Kassandra; Fujiwara, Yuko; Peng, Cong; Nguyen, Minh; Orkin, Stuart H., 2020, "Histone Demethylase Lsd1 is Required to Repress Hematopoietic Stem and Progenitor Cell Signatures During Blood Cell Maturation", https://doi.org/10.7910/DVN/AVCOF5, Harvard Dataverse, V1
Here, we describe that lysine-specific demethylase 1 (Lsd1/KDM1a), which demethylates histone H3 on Lys4 or Lys9 (H3K4/K9), is an indispensible epigenetic governor of hematopoietic differentiation. Integrative genomic analysis, combining global occupancy of Lsd1, genome-wide anal... |
Oct 30, 2020 -
Histone Demethylase Lsd1 is Required to Repress Hematopoietic Stem and Progenitor Cell Signatures During Blood Cell Maturation
Plain Text - 5.6 KB -
MD5: b7d4c660e900938f1304b9e842009733
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Oct 30, 2020 -
Histone Demethylase Lsd1 is Required to Repress Hematopoietic Stem and Progenitor Cell Signatures During Blood Cell Maturation
Plain Text - 9.8 KB -
MD5: dc7d4a2a64f40f1753da26edff4d9b8f
Investigation metadata |
Oct 30, 2020 -
Histone Demethylase Lsd1 is Required to Repress Hematopoietic Stem and Progenitor Cell Signatures During Blood Cell Maturation
Plain Text - 4.9 KB -
MD5: 6d937bb7110475efee80bccfd30347a9
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Oct 30, 2020 - Orkin Lab
Pinello, Luca; Xu, Jian; Orkin, Stuart H.; Yuan, Guo-Cheng, 2020, "ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells", https://doi.org/10.7910/DVN/FFPCJX, Harvard Dataverse, V1
We report a computational approach for investigation of chromatin state plasticity. We applied this approach to investigate an ENCODE ChIP-seq dataset profiling the genome-wide distribution of H3K27me3 in 19 human cell lines. We found that high plasticity regions (HPRs) can be di... |
Oct 30, 2020 -
ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells
Plain Text - 2.6 KB -
MD5: cbd7837b8da6960e2af8cb2e96307533
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Oct 30, 2020 -
ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells
Plain Text - 6.2 KB -
MD5: 03c6861209360f918b631f6b15c4bffd
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Oct 30, 2020 -
ChIP-seq analysis of chromatin state plasticity in primary human adult erythroid progenitor cells
Plain Text - 2.1 KB -
MD5: 04048e74a486c0866cf1709abec3f18e
Study metadata |